The human body is comprised of more than 200 cell types, and every one of these cell types arises from the zygote, the single cell that is formed when an egg is fertilized by a sperm. Within a few days, that single cell divides over and over again until it forms a blasto- cyst, a hollow ball of 150 to 200 cells that gives rise to every single cell type a human body needs to grown and survive, including the umbilical cord and the placenta that nourishes the developing fetus.

During the early stages of embryonic development, the cells remain relatively undifferentiated (immature) and possess the ability to become, or differentiate, into almost any tissue within the body. For example, cells taken from some section of an embryo that might have become part of the eye can be transferred into another section of the embryo and could develop into blood, muscle, nerve, or liver cells.” (source: medicinenet. com)

Embryonic stem cells are pluripotent, meaning they can give rise to every cell type in the fully formed body, but not the placenta and umbilical cord. These are “undifferentiated” stem cells, which have no identity. They then become partially undifferentiated. Before they assume the identity of a body part, they can still be assigned to any job to repair or replace anything elsewhere in the body. Originally designed and destined to become a particular body part, they are freelance handymen ready to go to work and become what is needed.

What is the Difference Between Totipotent, Pluripotent, and Multipotent?

“Totipotent cells can form all the cell types in a body, plus the extraembryonic, or placental cells. Embryonic cells within the first couple of cell divisions after fertilization are the only cells that are totipotent. Pluripotent cells can give rise to all of the cell types that make up the body; embryonic stem cells are considered pluripotent. Multipotent cells can develop into more than one cell type, but are more limited than pluripotent cells. Adult stem cells and cord blood stem cells are considered multipotent. These cells are usually limited to repairing and replenishing one particular type of tissue.” (source: Department of Health, Wadworth Center, NYSTEM, New York Stem Cell Science)

Role of Stem Cells

They guide the development from embryo to a living baby and then help that body heal itself throughout its lifetime. There is an abundance of stem cells during the early growth period and during the period the human is more active and in need of repair from use or accident. Over the years they become less and less as the body ages and their healing ability lessens. This is why the young heal right away and the elderly heal so slowly. In the younger period of the organism, Mother Nature is right there with stem cells at the ready to heal. They fix what is wrong with the tissue injured for that is their specific ability and job to do. They cannot go heal a neighboring muscle if their job is repairing some other body part.

Is it any wonder why older people have joint pains and joint damage that can’t heal and some end up with surgery? Surgery should be our last recourse as it can be fraught with complications like infections that can be disabling and even life threatening!

Enter Stem cell therapy. This wonderful modality is being used to boost or augment our body’s natural ability to heal. We can boost our own body’s ability to stimulate new stem cells and then also release more stem cells from our bone marrow to improve healing. High Dose Ozone can accomplish this boost to our healing. Changing our diet and lifestyle as mentioned above is great place to start. Adding needed micronutrients through the use of nutritional supplements to replace what we don’t get from our poor quality processed modern food supply is very important, and also an easy first step.

Use of Mesenchymal Stem Cells

Recently it was discovered that *mesenchymal stem cells are the most effective in repairing and replacing damaged and deteriorated knee, hip, and other joints that experience heavy wear and tear. The richest source of this pluripotent stem cell is from the umbilical cord and placenta. (*mesen- chymal (meh-ZE-kih-mul) cells develop into connective tissue, blood vessels, and lymphatic tissue.)

It is a treasure trove, with enough stem cell potential to heal many individuals over and over. With every child that is born there is an umbilical cord and placenta that are usually discarded. So, every birth delivers with it an abundant source of “regenerative medicine”. Parents are encouraged to have their newborn’s cord blood banked in case it is needed for the future treatment of a blood-borne disease. regenerative medicine science is one of the most exciting frontiers of health science simply because of the potential that it holds.

Recent clinical trials have used stem cells derived from cord blood to treat diabetes, cerebral palsy, and peripheral vascular disease with posititve results. It has also shown promise in treating heart disease, brain and spinal cord injuries, Parkinson’s disease, and much more. (source: National Center for Biotechnology Information, National Institutes of Health)

The Umbilical Cord and Wharton’s Jelly

The umbilical cord runs from an opening in the stomach of the fetus to the placenta which is attached to the lining of the womb wall during pregnancy. The cord has one vein and two arteries. The vein carries blood rich in oxygen and nutrients from the mother to the fetus.The arteries return deoxygenated blood and waste products, such as carbon dioxide back through the placenta.

Surrounding and protecting these vital blood vessels is a sticky, gel-like substance called Wharton’s Jelly. It was discovered that Wharton’s Jelly is rich in mesenchymal stem cells, which may be harvested in abundance for they are present in in every umbilical cord.

When mesenchymal stem cells derived from umbilical cord tissue are placed in an osteo- arthritic knee joint, they can potentially form cartilage cells. In addition to containing mesenchymal stem cells, the fluid contains many other growth factors (such as cytokines, hyaluronic acid) that benefit healing and regeneration. These growth factors can recruit other stem cells to the area, causing the existing cells to divide and stimulate the growth of nerves, blood vessels, and other supporting tissues. Similar studies have also found that amniotic tissue grafts used during spine surgeries lead to improved healing and less pain. When these grafts are applied to flesh wounds, they have been found to speed up healing and wound closure. (source: nih.gov)

Let Renew Help you manage joint inflammation, injury, and pain and restore more normal function with our regenerative medicine tools.

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